Potassium citrate may increase bone density

December 4, 2012

A study published in The Journal of Clinical Endocrinology & Metabolism shows that treatment with potassium citrate may increase bone mineral density and improve bone microarchitecture in healthy elderly people.

In the randomized, double-blind, placebo-controlled study, 201 elderly men and women (ages 65+) with normal baseline bone mineral density received either 60 milliequivalent/day (mEq/d) of Jungbunzlauer’s alkalizing tripotassium citrate (TPC) or placebo over 24 months. Both groups were supplemented with 500 mg calcium and 400 IU vitamin D3. The researcher’s objective was to assess the applicability of TPC and its effect on bones in the context of its ability to neutralize the acid load imposed by the modern Western diet.

After 24 months, the researchers found that taking TPC increased the bone mineral density of the lumbar spine (+1.7%). In addition, there were increases of trabecular densities in both radii and both tibiae, and decrease of fracture prediction score.

The authors conclude that TPC “… administered in a background of vitamin D and calcium supplements is well tolerated and constitutes an inexpensive intervention to increase bone mineral density and to improve bone microarchitecture in healthy elderly people with normal bone mass.”

Abstract