Citicoline may improve memory in the elderly

April 3, 2013

A study published in Clinical Interventions in Aging shows that citicoline, a nutrient found in every cell of the human body, may improve mild vascular cognitive impairment in elderly people who experience everyday lapses in memory.

The study, conducted by multiple health centers in Italy, included 349 patients with a mean age of 79.9. Participants who complained of memory lapses, but showed no signs of brain damage or Alzheimer’s, were given 500 mg of citicoline, produced by Kyowa Hakko Bio. The participants’ memory was tested at three, six, and nine months, and then compared to tests given to a control group taking no supplements.

Each group was given a series of questions called the Mini Mental State Examination (MMSE). Healthcare professionals use the MMSE common test to help diagnose and assess the progression and severity of memory problems. The researchers found a “significant difference” between the study and control groups at both three and six months. The control group MMSE scores declined significantly, while the citicoline group remained at baseline. This difference is an indicator that citicoline has neuroprotective effects. Participants taking citicoline also reported no adverse side effects.