When we reviewed the scientific basis for nutrigenomics, or personalized nutrition, in 2003 (Fogg-Johnson and Kaput, 2003), the human genome project was recently completed and an ever-increasing understanding of molecular-level effects of nutrients continued. The excitement caused by the unparalleled international collaborations to analyze the human genome and its variability (International HapMap Consortium, 2005) created lofty expectations in the medical and pharmaceutical sectors, food indust…

Moving Forward with Nutrigenomics

The “omics technologies” include high-throughput analyses of DNA (genomics), RNA (transcriptomics), protein (proteomics), or metabolites (metabolomics) using existing technologies.

Some scientific disciplines of nutrigenomics. Applications of nutrigenomics would also include public health, food science, cultural anthropology, and other disciplines

DNA sequencing chromatogram of CYP19 gene of five individuals who are homozygous for thymidine in both alleles (top and bottom), homozygous for cytosine C (end from top) or heterozygous (C/T). Blue is cytosine, red is thymidine, black is guanine, and green is adenosine.

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