Few molecules are as vital to human health yet so thoroughly misunderstood as vitamin D. There exists a tremendous gap between scientifically sound principles and clinical applications. Careful evaluations of clinical trials that examined health and disease relationships associated with vitamin D indicate that the actual daily requirement is closer to 1,000 IU instead of the current recommendation of 400 IU.
Bischoff-Ferrari et al. (2005, 2006) showed that the culmination of clinical evidence sup…