Oxidative stress and inflammation have been shown to be drivers of cognitive decline in the elderly. To investigate the potential effects of daily walnut consumption on cognition, researchers in California and Spain conducted a two-year study of 640 elders. Although little effect was found on healthy elderly adults, a positive effect was found on subgroups at higher risk, such as those who had smoked more and had lower baseline neuropsychological test scores.

Joan Sabaté, professor of nutrition and epidemiology at Loma Linda University School of Public Health and the study's principal investigator, said in a press release that the study was the largest and most well-controlled trial ever conducted on the effects of nuts on cognition, noting that “it could lead to better outcomes when conducted over longer periods of time. Further investigation is definitely warranted based on our findings, especially for disadvantaged populations, who may have the most to gain from incorporating walnuts and other nuts into their diet."

Sabaté’s research team was the first to discover the cholesterol-lowering effect of walnuts. Findings were first published in the New England Journal of Medicine in 1993.

Study

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