Citrus fruits, nearly 50 million metric tons of which were produced during the 2019–2020 season, contain an array of potential bioactive compounds in their peels, pulp, seeds, and juice. For more than 30 years, citrus-derived flavonoids have been studied for their potential health effects. Flavonoids are represented in six classes of compounds, namely flavones, flavonols, isoflavones, anthocyanidins, flavanones, and flavanols (Tripoli et al. 2007). The flavone moieties are present as eithe…