M.C. WILLIAMS

[DUE TO THE AMOUNT OF GRAPHICS IN THIS ARTICLE, IT IS ADVISED THAT YOU DOWNLOAD THE PDF VERSION FOR BETTER READABILITY]

It is now half of a century since passage of the 1958 Food Additives Amendment (FAA) to the Federal Food, Drug, and Cosmetic Act—Public Law 85-929, 72 Stat. 1784 (1958), codifi ed at 21 U.S.C. Sec. 348 (1988)—that exempted from food additive status those substances “generally recognized as safe” (GRAS) under conditions of intended use. In order for the use of a substance to qual…

GRAS FLAVORING SUBSTANCES 24

Figure 1. Alicyclic and heterocyclic alpha-ketoenols that form alpha-hydroxyenolates that readily complex with metal ions; Figure 2. Mechanism of in vitro furanone derivative oxidation

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