ARUN K. BHUNIA

Frequent food pathogen outbreaks and product recalls exert a huge economic burden on the United Sates economy, accounting for billions of dollars of losses each year. Application of broadband rapid pathogen screening tools to both pre-harvest and post-harvest products may be an effective strategy to produce safer foods. Spectral- or mammalian cell-based methods are ideal for high-throughput screening of microbes or toxins. Spectral-based light scattering sensors generate scatter signature of col…



Figure 1. Light scattering-based, high-throughput screening of Petri dish for bacterial pathogens in food.


Figure 2. General scheme for mammalian cell-based biosensor.

Figure 3. High-throughput screening strategy with mammalian cell-based biosensor. Left panel, Transmission electron microscopy images of collagen encapsulated healthy and Listeria monocytogenes-infected lymphocyte cell, Ped-2E9 in 3D scaffold.



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