Neotame: The Next-Generation Sweetener

A new sweetener derived from aspartame is thousands of times sweeter than sugar and does not have the undesirable taste characteristics common to some high-intensity sweeteners.

Food Technology Magazine | Article

INDRA PRAKASH, GLENN CORLISS, RAO PONAKALA,

GLEN ISHIKAWA

Neotame, a new high-intensity sweetener and flavor enhancer, is expected to receive Food and Drug Administration approval for use in foods and beverages in the United States soon. Since it will then be the newest approved sweetener in the U.S., it is appropriate to review its development, characteristics, and potential uses.

Overview
Neotame is a derivative of the dipeptide composed of the amino acids aspartic acid and phenylalanine. It is 7,000–13,000 times as sweet as sugar and 30–60 times as sw…


Fig. 2—Manufacture of neotame by reaction of aspartame with 3,3-dimethylbutyraldehyde


Fig. 3—Major pathway of degradation of neotame under hydrolytic conditions

Fig. 4—Sweetness intensity vs concentration of neotame in water

Fig. 7—Sweetness temporal profile of neotame compared to sucrose and aspartame at isosweet concentrations in water


Table 1—Typical neotame concentrations in various products when used as a sweetener



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In This Article

  1. Food Product Development
  2. Food Ingredients and Additives
  3. Sugars and Sweeteners
  4. Food Policy

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