Effects of the Human Genome Project are surfacing in anticipated and unanticipated areas. One of the key discoveries from the project is the existence of individual differences in gene sequences that result in differential response to environmental factors, such as diet. Those genetic differences, single nucleotide polymorphisms (SNPs, pronounced snips), are the key genetic enabler of the emerging scientific discipline called nutrigenomics or nutritional genomics. In the broad arena of health an…

Fig.1—Scientific disciplines contributing to nutrigenomics

Fig.2—Scientific principle of nutrigenomics

Table 1—Examples of potential vitamin-responsive SNPsa

Table 2—Some nuclear receptorsa,b

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